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William Osler Health System - Respiratory Therapy Resources: Home

Respiratory therapy information

Articles of Interest - Respiratory Care

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ROX Index

ROX Index with Patients on HFNC

ROX Index = (SpO2/FiO2)

                        Respiratory Rate

ROX index greater than or equal to 4.88 is predictive of HFNC success

HFNC failure was predicted with ROX index of less than or equal to:

  • 2.85 at 2 hours
  • 3.47 at 6 hours
  • 3.85 at 12 hours

Remember: If the Respiratory Rate and/or FiO2 increases a lot, the patient is deteriorating.

Clinical Practice Guidelines


Suggestions?  Email Christine Punton