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Knowledge Synthesis Guide

THP Knowledge Synthesis Service

What is Knowledge Synthesis?

  • summarizes all relevant studies on a specific question
  • combines the results of multiple studies, increasing our confidence in the results (power and precision) - there are 75 trials and 11 systematic reviews published per day! (1)
  • is central to evidence-informed decision making 
  • defines future research agendas (2)

Knowledge synthesis is the first step in Knowledge Translation:

"a dynamic and iterative process that includes synthesis, dissemination, exchange, and ethically-sound application of knowledge to improve the health of Canadians, provide more effective health services and products and strengthen the health care system." (3)

Let us help! 

Before getting started, please review our Policy and Levels of Service carefully.  



Please anticipate a minimum of 4-6 weeks for the delivery of search results (i.e. full translation of the initial search strategy) after the initial search strategy is approved by the project team. This timeline is also subject to change depending on the workload of the Library & Knowledge Services specialist.


1. The Principal Investigator must be affiliated with Trillium Health Partners. 
2. We only take on projects where a draft protocol is already established.
3. The team should have at least 3 members to ensure the project can be completed in a timely manner.

Services Not Offered

  • Duplicate removal
  • Full-text retrieval*
  • Grey literature searching*
  • Creating and maintaining PRISMA flowchart
  • Critical appraisal of retrieved articles
  • Project management
  • Data analysis

*Fee-based service: Please discuss with THP Library & Knowledge Services if you are interested in this service

References: (1) Bastian H, Glasziou P, Chalmers I. Seventy-five trials and eleven systematic reviews a day: how will we ever keep up? PLoS Med. 2010 Sep 21;7(9):e1000326. doi: 10.1371/journal.pmed.1000326. PMID: 20877712; PMCID: PMC2943439. (2) Kastner, M., Tricco, A.C., Soobiah, C. et al. What is the most appropriate knowledge synthesis method to conduct a review? Protocol for a scoping review. BMC Med Res Methodol 12, 114 (2012).; (3) Canadian Institutes of Health Research. Knowledge translation. Canadian Institutes of Health Research 2008.